LSM 880

With Airyscan You Enter a New World of Confocal Performance

  • Use a true confocal that gives you high sensitivity, improved resolution in x, y and z, and high speed in one system
  • Increase the resolution of your imaging: with Airyscan you resolve 140 nm laterally and 400 nm axially, at 488 nm
  • In the optional Virtual Pinhole Mode, you can decide even after the acquisition, which pinhole size best suits your application

Drosophila Retina Confocal 3D - Maximum intensity projection

Perform Quantitative Imaging

  • Perform gentle imaging of your samples, thanks to the homogeneous illumination with linear scanning, combined with a sensitive detection infrastructure
  • Working with identical pixel times and continuous scanner monitoring, you perform quantitative imaging at all speeds and scan modes
  • Get robust and reliable results, even from your most demanding single molecule imaging and analysis

Drosophila Retina Airyscan 3D - Maximum intensity projection

Increase Your Productivity

  • Save time on investigations into localization and interaction of proteins that require multiple fluorescent labels: You collect all these signals in one go
  • Perform simultaneous spectral detection in a single scan with the highest number of descanned or non descanned channels – including GaAsP technology
  • Take full advantage of large fields of view and the highest speed of any linear scanning confocal – up to 13 fps
Chloroplasts mov

The Airyscan Principle

A classic confocal microscope illuminates one spot on your sample to detect the emitted fluorescence signal. Out-of-focus emission light is rejected at a pinhole, the size of which determines how much of the airy pattern reaches the detector. You can increase the resolution by making the pinhole smaller, but signal-to-noise drops significantly since less valuable emission light is passing through. With Airyscan ZEISS introduces a new concept. Instead of throwing light away at the pinhole, a 32 channel area detector collects all light of an Airy pattern simultaneously. Each detector element functions as a single, very small pinhole. Knowing the beampath and the spatial distribution of each Airy pattern enables a very light efficient imaging: you can now use all of the photons that your objective collected.

It's up to you whether you use the additional information from your sample to get better signal-to-noise, resolution or speed. In the optional Virtual Pinhole Mode, you can decide even after the acquisition, which pinhole size best suits your application.

Chloroplasts of Elodea spec., 512 x 512 pixel at 10 frames per second with a pixel integration time of 0.36 microseconds


The Airyscan Principle

LSM880 Aryscan Beampath mov

LSM 880 Airyscan Beampath and Airyscan Principle

Lukas Microscope Service, Inc.            25715 N. Hillview Court, Mundelein, IL. 60060            847-673-2600

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